Abstract #4251

Multi-Task MR Simulation for Abdominal Radiation Treatment Planning: Technical Development

Junzhou Chen^1,2, Pei Han^1,2, Fei Han³, Zhehao Hu^1,2, Nan Wang^1,2, Wensha Yang⁴, Anthony G Christodoulou^1,2, Debiao Li^1,2, and Zhaoyang Fan^1,2,5

¹Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States, ²Department of Bioengineering, University of California, Los Angeles, Los Angeles, CA, United States, ³Siemens Medical Solutions USA, Inc., Los Angeles, CA, United States, ⁴Department of Radiation Oncology, University of Southern California, Los Angeles, CA, United States, ⁵Department of Radiology, University of Southern California, Los Angeles, CA, United States

MRI can provide superior soft tissue contrasts for radiation therapy planning. However, radiation planning in the abdomen is especially difficult because respiratory motion can cause misregistration across separate scans with different contrast weightings due to inconsistent breath holds or poor patient compliance. While some studies have produced volumetric and motion-resolved images, they are all limited to a single contrast which is suboptimal for radiation planning. To address these issues, we present a free-breathing MR imaging platform that produces multi-contrast and motion-resolved volumetric images using MR-multitasking, dedicated for radiation therapy planning, and under a 9:30 mins scan time.

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