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Abstract #4263

Acoustically transparent and low-profile head coil for high precision magnetic resonance guided focused ultrasound at 3 T

Isabelle Saniour1, Fraser Robb2, Victor Taracila2, Jana Vincent2, Henning U. Voss1, Michael G. Kaplitt3, J. Levi Chazen1, and Simone Angela Winkler1
1Weill Cornell Medicine, New York, NY, United States, 2MR Engineering, GE Healthcare, Aurora, OH, United States, 3Department of Neurological Surgery, Weill Cornell Medicine, New York, NY, United States

Magnetic resonance guided focused ultrasound (MRgFUS) is a non-invasive therapeutic modality for neurodegenerative diseases that allows real-time imaging of the targeted regions. However, MR image quality is poor and severely limits the technology due to the use of the body coil for focal targeting. Acoustic simulations demonstrated an acoustic transparency (signal loss <1%) of the coil when used for thalamic sonication. In vivo results showed increase of the SNR over the body coil by a factor of 7.3 and 7.6 in a brain image with and without the presence of the transducer, respectively.

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