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Abstract #4282

Where do streamlines come from? Seeding strategies impact on streamline distribution

Manon Edde1, Etienne St-Onge1, Antoine Théberge1,2, Guillaume Theaud1, Emmanuelle Renauld1, and Maxime Descoteaux1
1Sherbrooke Connectivity Imaging Lab (SCIL), Université de Sherbrooke, Sherbrooke, QC, Canada, 2Videos & Images Theory and Analytics Laboratory (VITAL), Université de Sherbrooke, Sherbrooke, QC, Canada

Tractography algorithms require a seeding map in which each point initiates one streamline. We can determine how many streamlines end in each voxel from one of their ends, but their initial point is unknown. We propose a method to compute the initial streamline points (IPS) in each voxel and evaluate their distribution depending on two strategies of seeding. With the surface-based interface, IPSs maps are more uniform along the cortex independently of the cortical volume, allowing a greater cortical coverage and specificity at the level of the cortical regions both at the whole-brain and bundle level.

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