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Abstract #4297

Surface-based Short Association Fibre Tractography

Dmitri Shastin1,2,3, Sila Genc1, Greg Parker1, Kristin Koller1, Chantal M.W. Tax1,4, John Evans1, Khalid Hamandi1,3,5, Derek Jones1,3, William Gray1,2,3, and Maxime Chamberland1
1Cardiff University Brain Research Imaging Centre (CUBRIC), Cardiff University, Cardiff, United Kingdom, 2Department of Neurosurgery, University Hospital of Wales, Cardiff, United Kingdom, 3BRAIN Biomedical Research Unit, Health & Care Research Wales, Cardiff, United Kingdom, 4Image Sciences Institute, University Medical Center Utrecht, Utrecht, Netherlands, 5Department of Neurology, University Hospital of Wales, Cardiff, United Kingdom

We propose a method of utilising mesh representations of cortical surfaces for generating tractograms of short association fibres facilitating a focused investigation into superficial white matter in health and disease. The method additionally allows to relate streamline metrics to surface topology in native space before registration for comparisons within and between subjects is performed. Our approach is applied to state-of-the-art test-retest data and shows good-to-excellent repeatability.

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