Meeting Banner
Abstract #4359

Intravoxel incoherent motion two-in-one MR sequence for ischemic stroke diagnosis. Initial clinical experience at 3T. 

Aude Pavilla1,2, Giulio Gambarota1, Alessandro Arrigo2, Mehdi Mejdoubi2, and Hervé Saint-Jalmes1,3
1Inserm, UMR 1099, Université de Rennes 1, LTSI, Rennes, France, 2Department of Neuroradiology, Pierre-Zobda-Quitman Hospital, University Hospital of Martinique, French West Indies, France, Fort-de-France, France, 3CRLCC, Centre Eugène Marquis, Rennes, France

This study aims to investigate the feasibility of simultaneously measuring perfusion and diffusion in the acute phase of ischemic stroke with the combined IntraVoxel Incoherent Motion and non-gaussian Diffusional Kurtosis Imaging (DKI-IVIM). For the fifteen patients enrolled, a significant decrease for the diffusion coefficient D and a significant increase in the kurtosis coefficient was observed in the infarcted lesions. Regarding the perfusion, the perfusion fraction f significantly decreased. Enhanced tissues heterogeneity was observable on reconstructed K maps. DKI-IVIM can provide with a clinically acceptable acquisition time both diffusion and perfusion characterization that might be of great interest for stroke diagnosis.

This abstract and the presentation materials are available to members only; a login is required.

Join Here