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Abstract #0017

Tensor-valued Encoding in the Human Heart In vivo

Irvin Teh1, David Shelley2, Ana-Maria Poenar1, Erica Dall'Armellina1, Sven Plein1, Jürgen E. Schneider1, and Filip Szczepankiewicz3
1Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, United Kingdom, 2Leeds Teaching Hospitals Trust, Leeds, United Kingdom, 3Clinical Sciences, Lund University, Lund, Sweden


Tensor-valued encoding holds great promise in enhancing specificity in myocardial characterisation relative to diffusion tensor imaging (DTI). However, its application in the heart is challenging due to motion and limited SNR. In this work, we employed optimized diffusion encoding waveforms with up to 2nd order motion compensation and compensation for concomitant gradient effects to demonstrate the first in vivo application of q-space trajectory imaging (QTI) in the human heart. Baseline myocardial measurements of microscopic fractional anisotropy, as well as isotropic and anisotropic mean kurtosis are reported for the first time in the heart.

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