Non-ECG-triggered, free-breathing simultaneous T1, T2, T2*, and fat-fraction quantification in the myocardium with MR Multitasking
Tianle Cao1,2, Nan Wang3, Alan C. Kwan4, Hsu-Lei Lee1, Xianglun Mao1, Yibin Xie1, Pei Han1,2, Hui Han1, Anthony G. Christodoulou1,2, and Debiao Li1,2
1Cedars Sinai Medical Center, Los Angeles, CA, United States, 2University of California, Los Angeles, Los Angeles, CA, United States, 3Radiology Department, Stanford University, Stanford, CA, United States, 4Department of Imaging and Cardiology, Cedars Sinai Medical Center, Los Angeles, CA, United States
Myocardium tissue characterization with multi-parametric mapping has gained increased clinical interest. Conventional methods require multiple breath-holding, ECG-triggered scans, which may result in potential image misregistration and patient fatigue. In this work, a free-breathing, non-ECG-triggered approach for simultaneous myocardial T1/T2/T2*/FF (fat-fraction) mapping is presented. Quantitative measurements from the proposed technique agreed with those from single-parameter references.
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