Detection of metabolites from human gallbladder poses some challenges due to its size and position. We compared breath-hold and respiratory triggered acquisition by 1H SVS STEAM sequence on patients in supine position at 3T. 14 peaks of bile components were detected using both acquisition setups. Quantification of metabolite concentrations, corrected with measured T2app relaxation times, showed results within the range of previously published data. STEAM sequence proved to be feasible for measurement of bile components at 3T in vivo, providing sufficient spectral quality for metabolite quantification in supine position with comparable results in both breath-hold and PACE navigated acquisition.
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