Perfusion Observations using Spherical Slice-shuffled Ultra-high-field MRI (POSSUM)
Jana Hutter1,2, Raphael Tomi-Tricot3, Thomas A Wilkinson1,2, Philippa A Bridgen1,2, Enrico DeVita2, Shaihan A Malik1,2, and Joseph V Hajnal1,2
1London Collaborative Ultra high field System (LoCUS), London, United Kingdom, 2Centre for Medical Engineering, King's College London, London, United Kingdom, 3Siemens Healthcare Limited, Frimley, United Kingdom
Spin tagging perfusion MR imaging allows the movement of blood in human tissue to be visualized and quantified non-invasively and contrast agent-free. Velicity-selection Arterial Spin Labeling (VSASL) relies on the velocity instead of the location for tagging. It is less dependent on the anatomy and coil coverage but includes directional dependence and can suffer from reduced SNR. POSSUM expands VSASL to spherical, directional-independant encoding and slice shuffling to enable more robust perfusion imaging at 7T.
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