Kidneys play a crucial role in glucose homeostasis via glucose reabsorption and glucose release into and glucose uptake from the circulation. We investigated the feasibility of measuring renal glucose uptake and metabolism with dynamic 3D DMI. A volunteer was scanned twice with two different ways of deuterated glucose administration: in the scanner and before scanning session. Similar glucose uptake was observed in the kidney and liver. We demonstrated the feasibility of measuring renal glucose uptake and metabolism with dynamic 3D DMI. This technique has potential to study the role of renal glucose uptake in glucose homeostasis in diabetes.
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