Head trauma is common in the pediatric population. Craniosynostosis is abnormal early fusion of a cranial suture, causing an irregular-shaped cranium.3D high-resolution head CT scans are commonly used in these pediatric patients to identify skull fractures and sutures. However, CT exposespediatric patients to ionizing radiationand increases risk of cancer. We developed a robust and automated deep learning method to convert MR images to pseudo-CT (pCT) that can facilitate translating MR cranial bone imaging into clinical practice. An average Dice Coefficient of 0.89 and mean absolute error of 72.45 HU between pCT and CT were achieved.
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