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Abstract #0209

A prospective patient study using pseudocontinuous Arterial Spin Labeling to detect pulmonary embolism: preliminary results of an ongoing study

Ferdinand Seith1, Cecilia Zhang1, Manuel Kolb1, Brigitte Gückel1, Rolf Pohmann2, Petros Martirosian3, and Ahmed E. Othman1,4
1Diagnostic and Interventional Radiology, University Hospital of Tübingen, Tübingen, Germany, 2High-Field MR Center, Max Planck Institute for Biological Cybernetics, Tübingen, Germany, 3Section on Experimental Radiology, University Hospital of Tübingen, Tübingen, Germany, 4Neuroradiology, University Hospital of Mainz, Mainz, Germany


We present preliminary results of a prospective study of 96 patients examined with pCASL-MRI of the lung with suspected pulmonary embolism. pCASL-MRI of the lung was acquired in a 1.5T scanner by labeling the pulmonary trunk during systole. Coronal, sagittal and axial images were acquired using a fast bSSFP sequence. Additionally, a mulit-slice coronal bSSFP imaging the whole lung was performed. Two blinded readers evaluated MR-images to detect pulmonary embolism and noted the diagnostic confidence (5=very good). Compared to CT, sensitivity and specificity were 0.971 and 0.951. The median diagnostic confidence was 5 in both readers (kappa 0.739).

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