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Abstract #0273

Adiabatic T mapping of the human myocardium at 3T.

Chiara Coletti1, Joao Tourais1, Telly Ploem1, Mehmet Akçakaya2, Christal van de Steeg-Henzen3, and Sebastian Weingärtner 1
1Department of Imaging Physics, TU Delft, Delft, Netherlands, 2Department of Electrical and Computer Engineering, University of Minnesota, Minneapolis, MN, United States, 3Medical Imaging and Radiation, Holland Proton Therapy Center, Delft, Netherlands

Synopsis

T-mapping constitutes a promising contrast-free alternative to LGE MRI for assessment of myocardial viability. However its applicability is hindered by susceptibility to B0 and B1+ field imperfections. In this work we propose a single breath-hold ECG-triggered adiabatically-prepared single-shot bSSFP T-mapping sequence. Bloch simulations are employed to identify optimal parameters for adiabatic pulses. The use of adiabatic preparations yields better resilience to system inhomogeneities and improved myocardium/blood contrast compared with conventional spin-lock modules, both in phantom and in-vivo. Thus, adiabatically-prepared sequences at 3T form a promising candidate for non-contrast evaluation of ischemic and non-ischemic cardiomyopathies.

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