Abstract #0275

Synthetic Multi-Contrast Late Gadolinium Enhancement Using Post-Contrast Cardiac MR Fingerprinting

Imran Rashid^1,2, Varun Rajagopalan^1,2, Sadeer Al-Kindi^1,2, Sanjay Rajagopalan^1,2, Nicole Seiberlich^3,4, and Jesse Ian Hamilton^3,4

¹Cardiology, University Hospitals Cleveland Medical Center, Cleveland, OH, United States, ²Medicine, Case Western Reserve University, Cleveland, OH, United States, ³Radiology, University of Michigan, Ann Arbor, MI, United States, ⁴Biomedical Engineering, University of Michigan, Ann Arbor, MI, United States

Synopsis

A technique is introduced using post-contrast cardiac Magnetic Resonance Fingerprinting (MRF) T₁ and T₂ maps to calculate synthetic late gadolinium enhancement (LGE) images with multiple contrast weightings, including bright-blood magnitude inversion recovery images, dark-blood T₂-prepared inversion recovery images, and a novel contrast weighting (optimized for each patient) designed to improve differentiation among viable myocardium, blood, and scar based on measured T₁ and T₂ values. Initial results are presented in fifteen patients with ischemic cardiomyopathy scanned at 1.5T using conventional LGE and MRF-derived multi-contrast LGE images.

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