Abstract #0364

High resolution diffusion-weighted MRI combining markerless prospective motion correction and locally low-rank constrained reconstruction

Ke Dai¹, Hao Chen¹, Sijie Zhong¹, Haoran Bai¹, Jiaxu Zheng², Xinyue Zhang², Shasha Yang², Tuoyu Cao², Lucio Frydman³, Chaohong Wang², and Zhiyong Zhang¹

¹School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China, ²United Imaging Healthcare, Shanghai, China, ³The Weizmann Institute of Science, Rehovot, Israel

Synopsis

High-resolution diffusion-weighted MRI is susceptible to head movement artifacts and background phase variations. We investigate a crucial combination of prospective motion correction and Spatial-angular local low rank (SPA-LLR) constrained reconstruction to obtain robust multi-shot high-resolution diffusion-weighted MRI under substantial motion. Prospective motion correction with optical markerless motion tracking is used to remove artifacts and blurring due to bulk motion whereas locally low-rank regularization is used to correct remaining artifacts due to the background phase variations from scan to scan. We present the results in healthy adult volunteers, demonstrating high-resolution diffusion-weighted images and FA images under different motion patterns with PMC.

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