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Abstract #0364

High resolution diffusion-weighted MRI combining markerless prospective motion correction and locally low-rank constrained reconstruction

Ke Dai1, Hao Chen1, Sijie Zhong1, Haoran Bai1, Jiaxu Zheng2, Xinyue Zhang2, Shasha Yang2, Tuoyu Cao2, Lucio Frydman3, Chaohong Wang2, and Zhiyong Zhang1
1School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China, 2United Imaging Healthcare, Shanghai, China, 3The Weizmann Institute of Science, Rehovot, Israel


High-resolution diffusion-weighted MRI is susceptible to head movement artifacts and background phase variations. We investigate a crucial combination of prospective motion correction and Spatial-angular local low rank (SPA-LLR) constrained reconstruction to obtain robust multi-shot high-resolution diffusion-weighted MRI under substantial motion. Prospective motion correction with optical markerless motion tracking is used to remove artifacts and blurring due to bulk motion whereas locally low-rank regularization is used to correct remaining artifacts due to the background phase variations from scan to scan. We present the results in healthy adult volunteers, demonstrating high-resolution diffusion-weighted images and FA images under different motion patterns with PMC.

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