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Abstract #0384

Combined 23Na and pTx-1H Imaging for Renal MRI at 7 Tesla

Christian R. Meixner1, Nico Egger1, Lena V. Gast1, Andreas K. Bitz2, Titus Lanz3, Ralph Kimmlingen4, Laurent Ruck1, Jürgen Herrler5, Michael Uder1, and Armin M. Nagel1,6
1Institute of Radiology, University Hospital Erlangen, Friedrich-Alexander- Universität Erlangen-Nürnberg (FAU), Erlangen, Germany, 2Faculty of Electrical Engineering and Information Technology, University of Applied Sciences, Aachen, Germany, 3Rapid Biomedical GmbH, Rimpar, Germany, 4Siemens Healthcare GmbH, Erlangen, Germany, 5Department of Neuroradiology, University Hospital Erlangen, Friedrich-Alexander- Universität Erlangen-Nürnberg (FAU), Erlangen, Germany, 6Division of Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany

Synopsis

In the human kidneys, the cortico-medullary sodium gradient plays an important role as it is essential for the concentration of urine and changes may indicate renal malfunction. However, quantitative 23Na MRI requires high-quality 1H MRI, since this facilitates co-registration and correction of partial volume effects, which is needed for body imaging in particular. We therefore show the feasibility of high-quality renal proton and sodium imaging using an 8Tx/16Rx 1H transceiver array that can be combined with a 23Na four-rung birdcage coil in a single setup.

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