This abstract addresses the challenges of 7T diffusion MRI associated with shorter T2/T2* and inhomogeneous B1+ field by implementing simultaneous multislice (SMS) parallel-transmit (pTx) slice-by-slice shimming in a readout-segmented diffusion-weighted sequence, RESOLVE. The benefits of pTx were compared to conventional single-transmit circularly polarized (CP) mode both with and without SMS using a matched high-resolution diffusion protocol in the same healthy volunteer. Slice-by-slice shimming significantly improves signal homogeneity while SMS opens the door for improved scan efficiency. The simplicity of slice-by-slice shimming and sequence integration makes this a practical solution for routine 7T imaging.
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