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Abstract #0455

Towards frequency robust tailored and universal pulses in the human heart at 7T

Christoph Stefan Aigner1, Sebastian Dietrich1, Felix Krüger1, Max Lutz1, and Sebastian Schmitter1,2,3
1Physikalisch-Technische Bundesanstalt (PTB), Braunschweig and Berlin, Germany, 2German Cancer Research Center (DKFZ), Medical Physics in Radiology, Heidelberg, Germany, 3University of Minnesota, Center for Magnetic Resonance Research, Minneapolis, MN, United States

Synopsis

This work demonstrates the design and application of frequency robust, subject-tailored or universal, non-selective kT-point pulses to achieve a homogeneous flip-angle within the 3D human heart at 7T across a 1400Hz wide frequency range that includes water and six fat frequencies. Frequency robust universal pulses were computed offline based on 31 3D B1+-maps and could be used in time-critical situations for calibration-free 3D heart flip-angle homogenization. Experimental data at 7T validates the flip-angle predictions and demonstrates successful excitation of fat and water in the human heart at 7T.

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