Conventional quantitative cartilage MRI (e.g., T1, T2, and T1ρ) approaches measure one single parameter at a time. Magnetic resonance fingerprinting (MRF) is a flexible, non-invasive measurement technique that simultaneously quantifies multiple MR parameters. In this work, we proposed a 3D-MRF sequence for the simultaneous volumetric acquisition of submillimetric proton density (PD) image and T1, T2, T1ρ, and B1+ maps of the knee cartilage in clinically feasible scan time (~11 minutes).
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