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Abstract #0665

Imaging lung water redistribution using 0.55T ultrashort echo time MRI

Felicia Seemann1, Ahsan Javed1, Rachel Chae1, Amanda Potersnak1, Scott Baute1, Kendall O’Brien1, Rajiv Ramasawmy1, Robert J Lederman1, and Adrienne E Campbell-Washburn1
1Cardiovascular Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, United States


Quantification of changes in lung water using MRI may provide clinical value in early diagnosis of heart failure. In this study, we demonstrate the ability of our 3D free-breathing spiral ultrashort-TE sequence to quantify and capture changes in lung water using a high-performance 0.55T MRI system. A phantom containing mixtures of water and deuterium oxide at varying concentrations was used to validate water density quantification. Our proposed approach captured the gravity-induced redistribution of lung water, achieved by imaging subjects in the supine and prone positions.

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