Abstract #0757

Variable Flip, Blip-Up and -Down Undersampling (VUDU) Enables Motion-Robust, Distortion-Free Multi-Shot EPI

Jaejin Cho^1,2, Tae Hyung Kim^1,2, Borjan Gagoski^2,3, Zijing Zhang⁴, Avery Berman^1,2, Congyu Liao⁵, and Berkin Bilgic^1,2,6

¹Athinoula A. Martinos Center for Biomedical Imaging, Charlestown, MA, United States, ²Department of Radiology, Harvard Medical School, Boston, MA, United States, ³Fetal-Neonatal Neuroimaging & Developmental Science Center, Boston Children’s Hospital, Boston, MA, United States, ⁴State Key Laboratory of Modern Optical Instrumentation, College of Optical Science and Engineering, Zhejiang University, Hangzhou, China, ⁵Radiological Sciences Laboratory, Stanford University, Palo Alto, CA, United States, ⁶Harvard/MIT Health Sciences and Technology, Cambridge, MA, United States

Synopsis

We demonstrate the motion-robustness of multi-shot diffusion imaging using VUDU (Variable flip, blip-Up, and -Down Undersampling) in the brain. VUDU employs FLEET-ordering to acquire all EPI shots of a given slice successively before proceeding to the next slice and maximizes the signal using variable flip angle (vfa) excitation. It also utilizes BUDA (Blip-Up and -Down Acquisition) to eliminate B₀ distortion and employs the Hankel low-rank regularization to address shot-to-shot phase variations. VUDU was able to provide high-fidelity diffusion-weighted images from in vivo data acquired during intentional head motion.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.