To identify the optimal model-based deconvolution process for DSC-MRI, four models of transit time distribution (TTD) were compared in terms of goodness and stability of fit, consistency of perfusion estimates, computational complexity, and robustness against noise. Although all models gave similar fits, the gamma function converged faster and more consistently to the global minimum, regardless of the initial guess. Moreover, it gave more accurate and precise perfusion estimates in the presence of noise. We conclude that the gamma function is the most suitable TTD model for perfusion analysis, and may prove useful in urgent clinical situations and multi-centre studies.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords