Abstract #0830

PSMA-PET vs mpMRI in prostate cancer patients with biochemical recurrence

Ingerid Skjei Knudtsen¹, Bendik Skarre Abrahamsen¹, Kirsten Margrete Selnæs², Mattijs Elschot¹, Sverre Langorgen³, Thomas Morten Keil³, Håkon Johansen³, Helena Bertilsson^4,5, Dag Linthoe Halvorsen⁴, Torgrim Tandstad^5,6, and Tone Frost Bathen¹

¹Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway, ²Department of Nuclear Medicine and Medical Physics, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway, ³Department of Radiology and Nuclear Medicine, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway, ⁴Department of Urology, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway, ⁵Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway, ⁶Cancer Clinic, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway

Synopsis

The PSMA prostate recurrence study is a multisenter prospective trial where the overall aim is to evaluate the diagnostic accuracy of 18F/68Ga-PSMA PET for detection of disease in patients with biochemical recurrence. In this preliminary analysis, we have compared the clinical imaging report of PET/CT/mpMRI to a separate evaluation of mpMRI where the radiologist was blinded to the PET results. Of 94 patients included so far, recurrent disease and/or distant metastasis was detected in 44 % (median PSA 0.4 ng/ml), according to the imaging protocol while the detection rate was 17 % for the mpMRI study scoring.

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