Free-Running 5D Flow MRI: Impact of Cardiac Temporal Resolution on Flow Quantification
Elizabeth K. Weiss1,2, Cynthia K. Rigsby3, Joshua D. Robinson3, Justin Baraboo1,2, Liliana Ma1,2, Mariana B. L. Falcão4, Christopher W. Roy4, Matthias Stuber4, and Michael Markl1,2
1Biomedical Engineering, Northwestern University, Evanston, IL, United States, 2Radiology, Feinberg School of Medicine, Chicago, IL, United States, 3Medical Imaging, Lurie Children's Hospital, Chicago, IL, United States, 4Radiology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland
The flexible reconstruction of 5D flow MRI data may be particularly beneficial in pediatric cases where cardiac cycle length varies greatly. We compared flow measurements from 5D flow and 2D phase contrast. 5D flow data was reconstructed using either a cardiac bin width of 40ms or that matching the 2D phase contrast reconstruction. We find excellent correlation of both 5D flow reconstructions with 2D phase contrast. There is overestimation of arterial flow measures by 5D flow, with most overestimation by the short temporal resolution reconstruction. Further study should additionally compare with 4D flow MRI.
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