Meeting Banner
Abstract #0901

4D flow MRI: Ex-vivo swine model allows distinction between flow patterns induced by aortic valve replacement and surgical pathway alone.

Maren Friederike Balks1, Hiroyuki Saisho2, Buntaro Fujita2, Tim Schaller2, Najla Sadat2, Stephan Ensminger2, Jörg Barkhausen1, Alex Frydrychowicz1, and Thekla Helene Oechtering3
1Department of Radiology and Nuclear Medicine, Universität zu Lübeck, Lübeck, Germany, 2Department of Cardiac and Thoracic Vascular Surgery, Universität zu Lübeck, Lübeck, Germany, 3Department of Radiology, University of Wisconsin, Madison, WI, United States


Hemodynamic outcome after aortic valve replacement (AVR) seems dependent on the type of replacement. The impact of the surgical pathway (aortotomy) itself on hemodynamics is still unclear. We proposed an ex-vivo swine model for comprehensive evaluation of aortic hemodynamics after different types of AVR with 4D flow MRI. Postoperative flow changes could be attributed not only to the implanted valve but also to the aortotomy. The new neocuspidization Ozaki procedure compared favorably to a biological valve as it induced fewer secondary flow patterns. Among the three different AVR methods, the mechanical valve allowed for hemodynamics that most closely approached physiology.

This abstract and the presentation materials are available to members only; a login is required.

Join Here