Nuclear overhauser enhancement (NOE) mediated chemical exchange saturation transfer (CEST) effect at -3.5 ppm has shown clinical interests in diagnosing tumors. Asymmetric analysis is a fast and simple method to measure and quantify the NOE effect, but has contamination from the downfield amide proton transfer (APT) effect at 3.5 ppm. In this abstract, we provide a new NOE quantification method using asymmetric analysis of CEST signals acquired with 2pi saturation pulses (2pi-CEST) which is also fast but has reduced contamination from the APT effect.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords