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Abstract #1101

T-Hex spirals for whole-brain fMRI at 5 frames per second: Image quality and BOLD sensitivity

Samuel Bianchi1, Maria Engel1, Jakob Heinzle2, Stefan Frässle2, Klaas E. Stephan2,3, and Klaas P. Pruessmann1
1Institute for Biomedical Engineering, ETH Zurich & University of Zurich, Zürich, Switzerland, 2Translational Neuromodeling Unit, University of Zurich & ETH Zurich, Zürich, Switzerland, 3Max Planck Institute for Metabolism Research, Cologne, Germany


fMRI is one of the driving technologies of neuroscience. During the past years, acquisition speeds below one second per whole-brain volume have been achieved. The recently proposed 3D T-Hex Spiral trajectories provide a powerful approach to enable even faster fMRI. Here, we demonstrate the feasibility of fMRI at a sampling rate of 5Hz with these trajectories at 7T. We acquired whole-brain images of one subject performing a visuo-motor task in the scanner. Our results indicate high BOLD sensitivity and fidelity of voxel timeseries. In total, we analyzed 9000 volumes obtained during 30min of scanning.

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