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Abstract #1103

Multi-Echo MR-Encephalography using Spherical Stack of Spirals Trajectories

Antonia Barghoorn1, Bruno Riemenschneider2, Wenchao Yang1, and Jürgen Hennig1
1Department of Radiology, Medical Physics, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany, 2Department of Artificial Intelligence in Biomedical Engineering, Friedrich-Alexander University Erlangen-N├╝rnberg, Erlangen, Germany

Synopsis

MREG allows very fast measurement of physiological signal changes at 100 ms acquisition time per volume. In order to investigate BOLD and non-BOLD contributions to the observed signal variations we have implemented an interleaved measurement scheme based on signal readout with two different echo times (15 and 36 ms). The interleaved implementation with alternating echo times increases the acquisition time to 200 ms, which still allows to investigate BOLD vs. non-BOLD signal changes at frequencies up to ±2.5 Hz. Preliminary measurements demonstrate the feasibility of ME-MREG in detecting both neuronal activations and resting-state functional connectivities.

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