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Abstract #1111

Model-Based Reconstruction with Automatic Differentiation for Single-Shot Myocardial T1 Mapping using Radial MOLLI with FLASH Readout

Xiaoqing Wang1,2, Moritz Blumenthal1, Nick Scholand1,2, and Martin Uecker1,2,3
1Institute for Diagnostic and Interventional Radiology, University Medical Center Göttingen, Göttingen, Germany, 2German Centre for Cardiovascular Research (DZHK), Partner Site Göttingen, Göttingen, Germany, 3Institute of Medical Engineering, Graz University of Technology, Graz, Austria


A nonlinear operator for radial MOLLI is constructed in BART, allowing accurate derivative calculation via automatic differentiation. The constructed nonlinear MOLLI operator is further integrated into a model-based reconstruction framework where myocardial $$$T_{1}$$$ maps are reconstructed directly from undersampled k-space data. Results on an experimental phantom and one healthy subject have demonstrated that high resolution ($$$1.0 \times 1.0 \times 6$$$ mm$$$^{3}$$$) myocardial $$$T_{1}$$$ maps can be achieved within 4 heartbeats with good accuracy and precision using the proposed method.

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