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Abstract #1119

Imaging cardiac purkinje fibers network using ihMT imaging on a clinical 1.5T scanner

Julie Magat1,2,3, Marylène Delcey4, Solenn Toupin4, Thomas Troalen4, Lucas Soustelle5, Andreea Hertanu5, Olivier Girard5, Guillaume Duhamel5, and Bruno Quesson1,2,3
1Université de Bordeaux, U1045, Bordeaux, France, 2IHU LIRYC, Pessac, France, 3INSERM U1045, Pessac, France, 4Siemens Healthcare SAS, Saint-Denis, France, 5Aix Marseille Univ, CNRS, CRMBM, Marseille, France


The Purkinje fiber network (PF) enables electrical impulses throughout the heart and initiate cardiac contraction. To characterize this network in 3D is of high importance to better understand cardiac arrhythmia mechanisms. This preliminary work performed at 1.5T using a high-resolution coil aims to evaluate the inhomogeneous Magnetization Transfer imaging method to visualize PF and differentiate them from the myocardium in a clinical setup. For the first time we obtained an ihMT contrast between a conductive fiber and myocardium at 1.5T on ex vivo sample with an isotropic resolution of 500 µm.

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