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Abstract #1124

Characterizing Brain Structural Differences in Hemodialysis Patients using MAP MRI

Wesley Thomas Richerson1, Brian Schmit1, and Dawn Wolfgram2
1Biomedical Engineering, Marquette Medical College of Wisconsin, Milwaukee, WI, United States, 2Department of Medicine, Medical College of Wisconsin, Wauwatosa, WI, United States


We collected brain MRI data using a custom, advanced diffusion sequence as well as typical T1 and T2 FLAIR anatomical images to characterize the differences between controls and Hemodialysis (HD) patients in a pilot study. We found decreased gray matter volume and thickness as well as increased white matter hyperintensity lesion volume in HD patients. Using the Mean Apparent Propagator technique, we found increased gray and white matter mean square displacement, white matter q space inverse variance and return to plane probability.

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