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Abstract #1155

Quality Assurance and Quality Control for HRMAS MRS Studies of Human Blood

Leo Cheng1, Matteo Sanchez-Dahl1, Isabella Muti1, JianXiang Weng1, and Anya Zhong1
1Massachusetts General Hospital, Charlestown, MA, United States


The lack of a standard universal protocol for sample preparation in MRS experiments results in instrumental and biological variability across reported studies. The purpose of this experiment is to evaluate a quality assurance protocol for performing HRMAS 1H MRS experiments with human biofluid samples, such as blood serum. The research objective is to determine if the spectral results measured from pooled samples can be used to assess results from individual samples as controls. These findings will help better develop efficient standard protocols for researchers and clinicians to use in the future.

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