Hyperpolarized 129Xe-MRI is prone to B1-inhomogeneity-induced signal artifacts, that often obscure pulmonary abnormalities. B1-inhomeogeneity can be corrected by calculating a flip-angle map and rescaling the images. Current methods to acquire a flip-angle map in 2D-spiral sequences require two-successive images to be collected in a single breath-hold, doubling scan duration. We demonstrate that flip-angle maps can be calculated from a single image acquisition using keyhole reconstruction. Furthermore, analytical methods can be used to minimize the amount of required oversampling. This approach enables accurate B1-artifact correction, with minimal impact to scan-duration, making it especially useful for short breath-hold studies.
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