Abstract #1220

Novel arterial spin labelling (ASL) brain injury symmetry assessment in retired professional athletes: a preliminary study

Ethan Danielli^1,2, Beatriz Padrela³, Mitchell Doughty^1,2, Jan Petr⁴, Henk Mutsaerts^3,5, and Michael D Noseworthy^1,2,6

¹School of Biomedical Engineering, McMaster University, Hamilton, ON, Canada, ²Imaging Research Centre, St. Joseph's Healthcare Hamilton, Hamilton, ON, Canada, ³Radiology and Nuclear Medicine, Amsterdam University, Amsterdam, Netherlands, ⁴Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany, ⁵Ghent Institute for Functional and Metabolic Imaging, Ghent University, Ghent, Belgium, ⁶Department of Electrical and Computer Engineering, McMaster University, Hamilton, ON, Canada

Synopsis

3D PCASL scans were acquired for seventeen aging, retired professional football players with a history of head traumas. Left, right and bilateral CBF and ASL spatial coefficient of variation (sCoV) values were examined for twelve concussion-related ROIs. A Z-scoring approach was applied, with outliers defined as mild, moderate, or severe injury burden (IB). An IB symmetry index was also calculated. Outliers were detected in all 12 ROIs, and the anterior parahippocampal gyrus and inferior frontal gyrus pars opercularis had the highest CBF and ASL sCoV IB, respectively. IB was not biased towards the left or right hemisphere.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.