Capturing 3D aortic motion over the heart cycle may give insight into a new biomarker for aortic disease and potentially improve the measurement of aortic hemodynamic parameters. An isotropic, free-breathing, respiratory-corrected 3D CINE balanced steady-state free precession imaging technique of the thoracic aorta was developed to investigate scan-rescan reproducibility of aortic diameter and displacement measures in nine healthy volunteers. Scan-rescan diameter was highly reproducible (CV<10% , ICC=0.85-0.86 and Pearson’s ρ=0.87) while displacement was more variable (CV=34-42%, ICC=0.34-0.50, ρ=0.59-0.72). These results are encouraging for future studies investigating aortic motion in health and aortopathy.
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