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Abstract #1229

Reproducibility of aortic diameter and displacement derived from free-breathing 3D balanced steady-state free precession CINE images at 3T

Renske Merton1, Eric M. Schrauben1, Gustav J. Strijkers2, Aart J. Nederveen1, and Pim van Ooij1,3
1Radiology and Nuclear Medicine, Amsterdam University Medical Centers, Amsterdam, Netherlands, 2Department of Medical Engineering & Physics, Amsterdam University Medical Centers, Amsterdam, Netherlands, 3University Medical Center Utrecht, Utrecht, Netherlands


Capturing 3D aortic motion over the heart cycle may give insight into a new biomarker for aortic disease and potentially improve the measurement of aortic hemodynamic parameters. An isotropic, free-breathing, respiratory-corrected 3D CINE balanced steady-state free precession imaging technique of the thoracic aorta was developed to investigate scan-rescan reproducibility of aortic diameter and displacement measures in nine healthy volunteers. Scan-rescan diameter was highly reproducible (CV<10% , ICC=0.85-0.86 and Pearson’s ρ=0.87) while displacement was more variable (CV=34-42%, ICC=0.34-0.50, ρ=0.59-0.72). These results are encouraging for future studies investigating aortic motion in health and aortopathy.

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