This work investigates the bias in the quantified relaxation times due to partial volume contributions of CSF for 23Na magnetic resonance fingerprinting (MRF) and reference methods. In simulations, a CSF contribution of only 10% resulted in an overestimation of 17% (31%) in T2l* in brain tissue for MRF (the reference). Further, a simple approach for CSF bias correction for 23Na MRF is proposed. This reduced the average absolute T1 deviation in brain tissue from 15% to 4%. The deviation in T2l* (T2s*) was reduced from 17% (35%) to 9% (5%). Finally, the correction was applied to in vivo MRF data.
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