Abstract #1276

Quantitative Sodium MRI of the Intervertebral Discs at 7T

Anna K. Scheipers^1,2, Daniel Peach³, Armin M. Nagel^1,4, Mark E. Ladd^1,2,5, and Tanja Platt¹

¹Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany, ²Faculty of Physics and Astronomy, Ruprecht Karl University of Heidelberg, Heidelberg, Germany, ³Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany, ⁴University Hospital Erlangen, Institute of Radiology, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany, ⁵Faculty of Medicine, Ruprecht Karl University of Heidelberg, Heidelberg, Germany

Synopsis

²³Na-MRI offers the possibility for non-invasive quantification of the sodium concentration in-vivo. The obtained functional information can provide interesting insights into the degeneration state of the human intervertebral discs¹ (IVDs). The presented work thus aimed to quantify the tissue sodium concentration (TSC) in the human intervertebral discs via ²³Na-MRI at 7T and to compare the obtained concentrations for two healthy volunteers after the course of one year. The estimate average concentration for all IVDs of both volunteers was found to be (96.5±8.8)mM and (113.6±9.5)mM, respectively.

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