Abstract #1291

MRI tractography-guided PET image reconstruction regularisation using connectome-based nonlocal means filtering

Zhuopin Sun¹, Georgios Angelis^1,2, Steve Meikle^3,4, and Fernando Calamante^1,4,5

¹School of Biomedical Engineering, The University of Sydney, Sydney, Australia, ²Australian National Imaging Facility, The University of Sydney, Sydney, Australia, ³Faculty of Medicine and Health, The University of Sydney, Sydney, Australia, ⁴Brain and Mind Centre, The University of Sydney, Sydney, Australia, ⁵Sydney Imaging, The University of Sydney, Sydney, Australia

Synopsis

Diffusion MRI (dMRI) can provide a wealth of information about brain microstructure and connectivity, but its use in PET-MRI image reconstruction has not been exploited. We incorporated dMRI-derived prior information as a regulariser into the iterative PET One-Step Late Maximum A Posteriori (OSLMAP) reconstruction algorithm. The proposed regularisation method has unique advantages of providing more informative and targeted denoising and regularisation based on the complementary structural connectivity information from dMRI.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.