In this study we present a 3D high resolution method for fast in vivo T1 and T2* mapping of fast relaxating tissues of the knee. All experiments were performed using a prototypical 3D spoiled gradient echo ultrashort echo time sequence with stack of spirals readout. T1 and T2* values of the mapping technique were validated by reference methods and literature values and showed good agreement for fast T1 and T2* values. The mapping technique enables T1 and T2* quantitation of fast relaxating tissues in a clinically appropriate measurement time of 9 minutes with a submillimeter spatial resolution (0.8mmx0.8mmx0.8mm).
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