T1 and T2 relaxometry provide important quantitative information and can serve as imaging biomarkers thanks to their sensitivity to pathology. However, quantitative imaging requires long scan times for high-resolution whole-brain coverage. Magnetization-prepared approaches combined with fast sequences allow for high isotropic resolution, but they are often biased due to other relaxation mechanisms than the one being probed. To account for this effect, we introduce QuantoRAGE: a new method that uses a T2-prepared inversion within an accelerated MP2RAGE sequence for simultaneous T1 and T2 mapping. Preliminary tests demonstrate the feasibility to obtain high-resolution simultaneous T1 and T2 relaxometry at 3T.
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