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Abstract #1378

Microstructural alteration of trigeminal nerve revealed by DTI and its correlation with vascular compression and pain

Tiantian Guo1, Chunqing Bu1, Chuanying Shi1, Daoqing Su2, Peng Wu3, and Chuanchen Zhang1
1Department of Radiology, Liaocheng People's Hospital, Liaocheng, China, 2Department of Neurosurgery, Liaocheng People's Hospital, Liaocheng, China, 3Philips Healthcare, Shanghai, China


Classical Trigeminal Neuralgia (CTN) is mainly caused by vascular compression of the trigeminal nerve. We analyzed the correlation between the fractional anisotropy (FA) / apparent diffusion coefficient (ADC) values of the bilateral trigeminal nerves and the degree of neurovascular compression (NVC) for CTN patients. Results shown the FA value is negatively correlated with the degree of NVC on the symptomatic side. FA values was lower if there was NVC on the asymptomatic side compared with no NVC. The correlation between FA and visual analogue scale (VAS) scores indicates that FA was a potential MR indicator for predicting patient clinical symptoms.

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