Abstract #1381

Comparison of MR diffusion based tractography methods for reconstruction of the facial nerve in pre-operative vestibular schwannoma

Caitlin O'Brien¹, Philip Touska², Elizabeth Gabriel¹, Haris Shuaib³, Karen Welsh⁴, and Steve Connor^2,5

¹Magnetic Resonance Physics, Guy’s & St. Thomas’ NHS Foundation Trust, London, United Kingdom, ²Department of Radiology, Guy’s & St. Thomas’ NHS Foundation Trust, London, United Kingdom, ³Clinical Scientific Computing, Guy’s & St. Thomas’ NHS Foundation Trust, London, United Kingdom, ⁴MRI, Guy’s and St. Thomas’ Hospitals & King’s College Hospital, London, United Kingdom, ⁵Neuroradiology, King’s College Hospital NHS Foundation Trust, London, United Kingdom

Synopsis

Four DWI tractography acquisitions are trialled across 13 pre-surgical patients with vestibular schwannomas: single shell EPI, ZOOMit, RESOLVE, & multi-shell RESOLVE, with an aim to reconstruct the path of the facial nerve. Data is analysed using MRtrix using multi-shell multi-tissue constrained spherical deconvolution (MSMT-CSD) and the probabilistic iFOD2 algorithm. The best reconstruction was achieved using a 30 direction multi-shell (b = 0, 300, 1000 s/mm²) RESOLVE acquisition scheme.

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