Abstract #1381
Comparison of MR diffusion based tractography methods for reconstruction of the facial nerve in pre-operative vestibular schwannoma
Caitlin O'Brien1, Philip Touska2, Elizabeth Gabriel1, Haris Shuaib3, Karen Welsh4, and Steve Connor2,5
1Magnetic Resonance Physics, Guy’s & St. Thomas’ NHS Foundation Trust, London, United Kingdom, 2Department of Radiology, Guy’s & St. Thomas’ NHS Foundation Trust, London, United Kingdom, 3Clinical Scientific Computing, Guy’s & St. Thomas’ NHS Foundation Trust, London, United Kingdom, 4MRI, Guy’s and St. Thomas’ Hospitals & King’s College Hospital, London, United Kingdom, 5Neuroradiology, King’s College Hospital NHS Foundation Trust, London, United Kingdom
Synopsis
Four DWI tractography acquisitions are trialled across 13 pre-surgical patients with vestibular schwannomas: single shell EPI, ZOOMit, RESOLVE, & multi-shell RESOLVE, with an aim to reconstruct the path of the facial nerve. Data is analysed using MRtrix using multi-shell multi-tissue constrained spherical deconvolution (MSMT-CSD) and the probabilistic iFOD2 algorithm. The best reconstruction was achieved using a 30 direction multi-shell (b = 0, 300, 1000 s/mm2) RESOLVE acquisition scheme.
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