Quantification and visualization of aneurysm treatment outcome with signal enhancement on Black Blood MRI.
Mariya S. Pravdivtseva1, Fritz Wodarg2, Jana Korte3, Philipp Berg3, Jan-Bernd Hövener1, Olav Jansen2, and Naomi Larsen2
1Department of Radiology and Neuroradiology, Section Biomedical Imaging, Molecular Imaging North Competence Center (MOIN CC), University Medical Center Schleswig-Holstein (UKSH), Kiel University, Kiel, Germany, 2Department of Radiology and Neuroradiology, University Medical Center Schleswig-Holstein (UKSH), Kiel, Germany, 3Research Campus STIMULATE, University of Magdeburg, Magderburg, Germany
Intracranial aneurysm is a life-threatening disease that can be treated with flow-modulating devices (FMDs) by reducing aneurysm blood flow. Aneurysms might rupture after treatment, thus biomarker of successful treatment is needed. Flow MRI can detect flow reduction, however, it is impaired by metal artifacts from FMDs. Black-blood (BB) MRI is less sensitive to metal artifacts and often results in poor slow-flow suppression. We hypothesize that BB contrast changes after aneurysm treatment. Here, after placing FMDs in 3D-printed aneurysm models, an enhanced signal was found on BB MRI, associated with reduced aneurysmal flow after flow modulation and thus possible treatment success.
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