Abstract #1397

Improved 3D stack-of-spiral UTE pulmonary imaging at 0.55T using iterative concomitant field and motion corrected reconstruction (iCoMoCo)

Ahsan Javed¹, Rajiv Ramasawmy¹, Joel Moss², Waqas Majeed³, Pan Su³, Thomas Benkert⁴, Himanshu Bhat³, Ashkan Malayeri⁵, and Adrienne E. Campbell-Washburn¹

¹Cardiovascular Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, United States, ²Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, United States, ³Siemens Medical Solutions USA Inc, Malvern,, PA, United States, ⁴Siemens Healthcare GmbH, Erlangen, Germany, ⁵Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, United States

Synopsis

Lung MRI using a high-performance 0.55T system offers reduced susceptibility artifacts, but high resolution imaging is challenged by low proton density, reduced signal-to-noise ratio, and concomitant-fields. 3D spiral acquisitions can be used for improved efficiency and SNR, at the expense of concomitant field related blurring. We present a self-gated, ultra-short echo time, stack-of-spirals acquisition with an efficient inline iterative reconstruction (<15 min) that incorporates both concomitant-field and motion-correction to enable robust high-resolution lung imaging at 0.55T. Our optimized and efficient imaging method is applied to improve image quality in healthy volunteers, patients with lung nodules, and patients with lymphangioleiomyomatosis (LAM).

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