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Abstract #1457

Dynamic Contrast Enhanced MR perfusion of the Spinal Cord with radial streaking artefacts reduction at 3T: Preliminary results and applications

Guillaume Frébourg1,2,3, Kaissar Farah4, Thomas Troalen5, Lauriane Pini1,3, Aurélien Destruel1,2,3, Stéphane Fuentes4, Maxime Guye1,3, and Virginie Callot1,2,3
1Aix-Marseille University, CNRS, CRMBM, Marseille, France, 2iLab-Spine International Associated Laboratory, Marseille-Montréal, France, 3AP-HM, Hôpital de la Timone, CEMEREM, Marseille, France, 4AP-HM, Hôpital Timone, Neurosurgery Dept., Marseille, France, 5Siemens Healthcare SAS, Saint-Denis, France


3T T1-GRASP acquisition combined with an optimized dynamic radial streaking artefacts reduction have been set up to analyze Dynamic Contrast Enhanced MRI (DCE) over time and spinal cord levels. Acquisition with Gd-injection using the best temporal resolution parameters have been applied on two healthy volunteers and one patient showing perfusion dysfunction with compression. Semi-quantitative parameters (SQP) have been calculated in different regions of interest along the cervical levels and voxel-wise to provide SQP axial mapping of the spinal cord.

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