Abstract #1457

Dynamic Contrast Enhanced MR perfusion of the Spinal Cord with radial streaking artefacts reduction at 3T: Preliminary results and applications

Guillaume Frébourg^1,2,3, Kaissar Farah⁴, Thomas Troalen⁵, Lauriane Pini^1,3, Aurélien Destruel^1,2,3, Stéphane Fuentes⁴, Maxime Guye^1,3, and Virginie Callot^1,2,3

¹Aix-Marseille University, CNRS, CRMBM, Marseille, France, ²iLab-Spine International Associated Laboratory, Marseille-Montréal, France, ³AP-HM, Hôpital de la Timone, CEMEREM, Marseille, France, ⁴AP-HM, Hôpital Timone, Neurosurgery Dept., Marseille, France, ⁵Siemens Healthcare SAS, Saint-Denis, France

Synopsis

3T T1-GRASP acquisition combined with an optimized dynamic radial streaking artefacts reduction have been set up to analyze Dynamic Contrast Enhanced MRI (DCE) over time and spinal cord levels. Acquisition with Gd-injection using the best temporal resolution parameters have been applied on two healthy volunteers and one patient showing perfusion dysfunction with compression. Semi-quantitative parameters (SQP) have been calculated in different regions of interest along the cervical levels and voxel-wise to provide SQP axial mapping of the spinal cord.

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