A Hybrid IVIM-DTI Model with Optimized Acquisition Time
Sam Sharifzadeh Javidi1 and Hamidreza Salighehrad2,3
1Department of Medical Physics and Biomedical Engineering, Tehran University of Medical Sciences, Tehran, Iran (Islamic Republic of), 2Department of Medical Physics and Biomedical Engineering, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran (Islamic Republic of), 3Quantitative MR Imaging and Spectroscopy Group, Research Center for Molecular and Cellular Imaging, Tehran University of Medical Sciences, Tehran, Iran (Islamic Republic of)
IVIM-DTI imaging is capable of revealing both structural and functional maps. We conduct this study to address the long acquisition time of IVIM-DTI imaging and the inaccuracy of estimates of the model’s outputs. Diffusion-weighted images were acquired at 11 b-values and 64 orientations. We used the Kalman filter to reach higher accuracy in a lower number of images. The resulting maps indicated that diffusion maps and pseudodiffusion maps for a healthy case are of highly visual similarity. Our results also confirmed that achieving a good accuracy is possible with just half number of images.
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