Abstract #1509
Characterization of relationship between MR microstructural parameters and memory in older subjects
Scott Peltier1,2, Michelle Karker1, Jon-Fredrik Nielsen1,2, Navid Seraji-Bozorgzad3, Henry Paulson3, Bruno Giordani3,4, and Benjamin M. Hampstead4,5
1Biomedical Engineering, University of Michigan, Ann Arbor, MI, United States, 2Functional MRI Laboratory, University of Michigan, Ann Arbor, MI, United States, 3Neurology, University of Michigan, Ann Arbor, MI, United States, 4Psychiatry, University of Michigan, Ann Arbor, MI, United States, 5Mental Health Service, VA Ann Arbor Healthcare System, Ann Arbor, MI, United States
Synopsis
This work examined the relationship between white matter microstructure parameters calculated by NODDI and a composite measure of memory function. Connectome predictive modeling was done on fractional anisotropy, orientation dispersion, and neurite density maps. Significant relationships were found for all parameters, with orientation dispersion having the highest correlation between predicted and observed memory scores.
This abstract and the presentation materials are available to members only;
a login is required.
Join Here
