For patients with clinical suspicion for significant prostate cancer, the decision to undergo prostate biopsy can be supported by calculating the individual risk profile using demographic and clinical information along with multiparametric MRI assessment. We could show that the prediction performance of an established risk calculator remained stable after substituting manual PI-RADS scores for assessments from a fully automated deep learning system. Combining deep learning and PI-RADS resulted in significant improvements over using only PI-RADS. Complementary information that deep learning models are able to extract enable synergies with radiologists to improve individual risk predictions.
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