Meeting Banner
Abstract #1529

Simplified fast multislice T1app mapping for improved cerebral blood flow arterial spin labeling MRI

Yang Ji1, Dongshuang Lu1, and Phillip Zhe Sun1,2
1Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States, 2Department of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, GA, United States


Given the association between MT and longitudinal relaxation rate (1/T1), we hypothesized that T1app, under RF saturation, can be estimated from T1 to improve CBF quantification. Using Wistar rats, we showed that the T1app over T1 ratiometric map (i.e., T1app/T1) is homogeneous despite large regional variation in T1 and T1app maps. Therefore, we postulated that T1app map could be estimated from the routine T1 map instead of T1app, which is cumbersome and not straightforward. A fast T1app estimation provides satisfactory Cerebral blood flow (CBF) measurement across the brain, not affected by the concomitant MT effect.

This abstract and the presentation materials are available to members only; a login is required.

Join Here