Given the association between MT and longitudinal relaxation rate (1/T1), we hypothesized that T1app, under RF saturation, can be estimated from T1 to improve CBF quantification. Using Wistar rats, we showed that the T1app over T1 ratiometric map (i.e., T1app/T1) is homogeneous despite large regional variation in T1 and T1app maps. Therefore, we postulated that T1app map could be estimated from the routine T1 map instead of T1app, which is cumbersome and not straightforward. A fast T1app estimation provides satisfactory Cerebral blood flow (CBF) measurement across the brain, not affected by the concomitant MT effect.
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