We have shown that it is feasible to perform POCE MRS in the human brain at 7T during a uniformly labeled [U-13C] glucose infusion in three healthy volunteers, using a 13C birdcage head coil combined with 8 transmit-receive 1H antennas with a 32-channel 1H receive array. STEAM-POCE and sLASER-POCE provided similar sensitivity for the [4-13C]-Glx-H4 signals. POCE examinations could be performed in two locations, i.e. the frontal and occipital lobe, in one session, allowing them to be easily merged with 1H MRI.
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